This fresco is in the Refectory of St. Clare. The painting illustrates the events that transpired when Pope Gregory IX visited the Poor Clares and requested to dine with them. It is recorded that Pope Gregory had profound respect and admiration for St. Clare and often called on her to pray for him. At this visit, the Pope asked Clare to bless the meal and after she prayed a cross formed on the top of each loaf of bread.

You can see the surprise on the faces of the Pope and his companions at this miraculous event, not at the hand of the Pope, but of Clare! Clare’s right hand is raised in the posture of speaking something that is significant. Rays of light are painted entering through the window and pointed toward Clare. In religious art, these rays are representative of the actions of the Holy Spirit. Clare and her sisters are painted in the habits consistent of their Order, grey tunics with a black veil.